TEST DESCRIPTION

Cytokines and chemokines of the female reproductive tract are released to induce an innate immune inflammatory response to sexually transmitted pathogens and resident members of the pathogenic vaginal microbiota. Excess levels of inflammation may lead to cellular damage and increased mucosal vulnerability to sexually transmitted and viral infections. Furthermore, activation of local immunity is a marker for microbiome dysbiotic disorders leading to infertility, implantation failure, chemical pregnancies and recurrent early pregnancy loss, as well as, pregnancy complications including premature rupture of the membranes and premature birth.

The FERTILYSIS Inflammation Index test is an innovative solution for the early detection of local inflammation of the vaginal epithelium

This test allows us to assess the state of the local (mucosal) immunity by analyzing expression levels of key genes of the immune response, the assessment of local cytokine profile and the ratio of pro-inflammatory to immunosuppressive cytokines, as a measure of local inflammation.

Compared to the traditional methods for indirectly diagnosing local inflammation, the FERTILYSIS Inflammation Index test is more sensitive, and capable of detecting an inflammatory reaction at the initial stage, before an increase in the number of leukocytes, at an early stage of clinical manifestations.

SPECIMEN TYPE: Vaginal Swab (x2)

SAMPLE COLLECTION: Self collected

SAMPLE STORAGE & SHIPPING: Storage in the freezer. Shipping at ambient temperature.

RESULT TURNAROUND TIME: Depending on how busy the lab is, we estimate you will get your results within 10 business days from the day your sample reaches us *.

* Please be advised that the turnaround time for specialized diagnostic tests is indicative and not guaranteed and may be extended due to a variety of factors, including but not limited to need for additional clinical evaluation of results, repeat of analysis in cases of unclear or ambiguous results and need for resampling in case of inadequate specimen quality. Therefore, the results will be available in the indicated timeframe as long as there are no additional overheads, as stated above, that may extend turnaround time.