TEST DESCRIPTION

Thrombophilia is a condition characterized by an increased tendency to develop blood clots. Pregnancy itself is considered a prothrombotic state due to various changes in the body that promote blood clotting, including increased clotting factors, decreased natural anticoagulants, and alterations in blood flow and vessel structure.

During pregnancy, the process of spiral artery remodeling takes place in the uterus, which is essential for maintaining adequate blood flow to the placenta and supporting the developing fetus. This remodeling allows for increased blood flow, ensuring the delivery of vital nutrients and oxygen to the fetus. However, if an underlying thrombophilia is present, it can disrupt this normal remodeling process.

Thrombophilia can impede the proper blood flow through the spiral arteries, resulting in insufficient blood supply to the placenta and fetus. This can lead to complications such as placental insufficiency, preeclampsia, intrauterine growth restriction, and an increased risk of miscarriage. Additionally, thrombophilia has been associated with reduced success rates in implantation and pregnancy following assisted reproductive techniques like IVF.

To mitigate these risks, it is crucial for pregnant women with known thrombophilia to receive close monitoring from healthcare providers. They may require anticoagulant medications, such as baby aspirin and low molecular weight heparin, to reduce the likelihood of blood clots, ensure proper blood flow to the placenta and fetus, and improve fertility outcomes. Consulting with healthcare professionals experienced in managing thrombophilia during pregnancy is essential to determine the most appropriate treatment approach.

SPECIMEN TYPE: Blood sample is needed for this test. 1 x Peripheral Blood /EDTA (Lavender Vacutainer) (2ml total) sample is required.

SAMPLE COLLECTION: For collection of blood samples, you should arrange for a healthcare professional to draw the bloods for you according to the instructions, in a licensed medical facility.

SAMPLE STORAGE & SHIPPING: Following collection, blood samples can be stored in the refrigerator until pick up and shipped at ambient (room) temperature (no icepacks required). Samples can be stored/travel safely for a few days under these conditions without problems. However, we advise that you arrange sample collection and shipping on a Monday or a Tuesday so that we ensure timely delivery to our lab and to avoid running over a weekend in cases of an unexpected delay.

RESULT TURNAROUND TIME:  Because this test requires extensive analysis, depending on how busy the lab is, we estimate you will get your results in 10 business days from the day your sample reaches us *. 

* Please be advised that the turnaround time for specialized diagnostic tests is indicative and not guaranteed and may be extended due to a variety of factors, including but not limited to need for additional clinical evaluation of results, repeat of analysis in cases of unclear or ambiguous results and need for resampling in case of inadequate specimen quality. Therefore, the results will be available in the indicated timeframe as long as there are no additional overheads, as stated above, that may extend turnaround time.